Expresión de búsqueda: CORE BINDING FACTOR ALPHA SUBUNITS 
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Descriptor Inglés:   Core Binding Factor alpha Subunits 
Descriptor Español:   Subunidades alfa del Factor de Unión al Sitio Principal 
Descriptor Portugués:   Subunidades alfa de Fatores de Ligação ao Core 
Sinónimos Inglés:   Core Binding Factor alpha Proteins  
Categoría:   D12.776.930.155.200
Definición Inglés:   A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression. 
Nota Histórica Inglés:   2006(1987) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   51175 
Identificador Único:   D050657 

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